Mouthwash Containing Cetylpyridinium Chloride and Zinc Lactate Shows Enhanced Antiplaque and Antigingivitis Efficacy

Fig 1. Consolidated Standards of Reporting Trials (CONSORT) flow diagram.

Fig 2. Mean Plaque Index Scores Over Time. (A) Mean whole-mouth plaque index scores over time. (B) Mean interproximal plaque index scores over time. (C) Mean gumline plaque index scores over time. (D) Mean plaque severity scores over time. Statistical analysis was performed via paired t-test for within-treatment comparisons to baseline: a = P < .05 compared to CPC + Zn treatment group baseline; b = P < .05 compared to CPC treatment group baseline; c = P < .05 compared to placebo treatment group baseline. Statistical analysis was performed via analysis of covariance (ANCOVA) for between-treatment comparisons of baseline-adjusted means: ** P < .05.

Fig 3. Mean Gingival Index Scores Over Time. (A) Mean whole-mouth gingival index scores over time. (B) Mean interproximal gingivitis scores over time. (C) Mean gingival bleeding scores over time. Statistical analysis was performed via paired t-test for within-treatment comparisons to baseline: a = P < .05 compared to CPC + Zn treatment group baseline; b = P < .05 compared to CPC treatment group baseline; c = P < .05 compared to placebo treatment group baseline. Statistical analysis was performed via ANCOVA for between-treatment comparisons of baseline-adjusted means: ** P < .05.